ASSOCIATION OF SEROPOSITIVITY FOR CMV IGM AND IGG WITH ADVERSE PREGNANCY OUTCOME

• Published in: Pakistan Armed Forces medical journal Vol. 71; no. 3; pp. 831 - 35
• Main Authors: Amna, Ambreen, Nadeem, Farkhunda, Fahim, Amin, Jatoi, Altaf Hussian, Abbas, Kanwal, Anas, Sumayya
• Format: Journal Article
• Language: English
• Published: Rawalpindi Knowledge Bylanes 30.06.2021; AsiaNet Pakistan (Pvt) Ltd; Army Medical College Rawalpindi
• Subjects: adverse pregnancy outcome; Age groups; Antibodies; Cytomegalovirus; Education; Fetuses; Gestational age; Health aspects; Industrialized nations; Infection; Infections; intrauterine fetal death; Miscarriage; Pregnancy; Pregnant women; preterm labour; Socioeconomic factors; Stillbirth; United States > US
• ISSN: 0030-9648; 2411-8842
• DOI: 10.51253/pafmj.v71i3.2928

Objective: To find out the prevalence of antibodies against cytomegalovirus and their association with adverse pregnancy outcome in women, at Isra University Hospital Hyderabad. Study Design: Cross-sectional study. Place and Duration of Study: Department of Gynaecology & Obstetrics, Isra University Hospital (IUH) Hyderabad, from Jan to Jun 2018. Methodology: Cytomegalovirus IgM and IgG antibodies in 305 women of reproductive age group were measured using the Enzyme Linked Fluorescent Assaysystem kit. Results: The combined positivity of anti cytomegalovirus IgG and IgM antibodies was 93 (30.40%). About 37 (37.37%) and 28 (34.14%) women were found to be seropositive for cytomegalovirus antibodies who had history of spontaneous miscarriage and recurrent miscarriages respectively. Conclusion: Higher association of seropositivity for cytomegalovirus IgM and IgG with bad obstetrical history and low economy was found.