Viability of shear wave elastography to predict mechanical/ultimate failure in the anterolateral and medial collateral ligaments of the knee

• Published in: Journal of biomechanics Vol. 174; p. 112264
• Main Authors: Wei, Yi, Alzouhayli, Kenan, Schilaty, Nathan D., Hooke, Alexander W., Sellon, Jacob L., Bates, Nathanial A.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Ltd 01.09.2024; Elsevier Limited
• Subjects: Aged; Aged, 80 and over; Anterior cruciate ligament; Anterolateral Ligament; Biomechanical Phenomena; Cadaver; Cadavers; Collateral Ligaments - diagnostic imaging; Collateral Ligaments - physiology; Collateral Ligaments - physiopathology; Elasticity Imaging Techniques - methods; Elastography; Failure; Female; Humans; Hypotheses; Injuries; Injury prevention; Knee; Knee Joint - diagnostic imaging; Knee Joint - physiology; Ligament; Ligaments; Male; Material properties; Mechanical properties; Mechanical Testing; Medial Collateral Ligament, Knee - diagnostic imaging; Medial Collateral Ligament, Knee - injuries; Medial Collateral Ligament, Knee - physiopathology; Middle Aged; Modulus of elasticity; Range of motion; Shear; Stiffness; Strain; Stress, Mechanical; Tendons; Ultrasonic imaging; Viscoelasticity; Anterolateral Ligament; Ligament; Mechanical Testing; Elastography; Anterior cruciate ligament
• ISSN: 0021-9290; 1873-2380; 1873-2380
• DOI: 10.1016/j.jbiomech.2024.112264

The purpose of this study was (1) to determine the utility of shear wave elastography as a predictor for the mechanical failure of superficial knee ligaments and (2) to determine the viability of shear wave elastography to assess injury risk potential. Our hypothesis was that shear wave elastography measurements of the anterolateral ligament and medial collateral ligament would directly correlate with the material properties and the mechanical failure of the ligament, serving as a prognostic measurement for injury risk. 8 cadaveric specimens were acquired, and tissue stiffness for the anterolateral ligament and medial collateral ligament were evaluated with shear wave elastography. The anterolateral ligament and medial collateral ligament were dissected and isolated for unilateral mechanical failure testing. Ultimate failure testing was performed at 100 % strain per second after 50 cycles of 3 % strain viscoelastic conditioning. Each specimen was assessed for load, displacement, and surface strain throughout failure testing. Rate of force, rate of strain development, and Young’s modulus were calculated from these variables. Shear wave elastography stiffness for the anterolateral ligament correlated with mean longitudinal anterolateral ligament strain at failure (R2 = 0.853; P<0.05). Medial collateral ligament shear wave elastography calculated modulus was significantly greater than the anterolateral ligament shear wave elastography calculated modulus. Shear wave elastography currently offers limited reliability in the prediction of mechanical performance of superficial knee ligaments. The utility of shear wave elastography assessment for injury risk potential remains undetermined.