Blood levodopa levels and unified Parkinson's disease rating scale function: with and without exercise
We studied 10 regular exercising men with Parkinson's disease on levodopa (LD) under two conditions--no exercise and vigorous exercise started 1 hour after LD ingestion. We compared LD levels and motor scores on the Unified Parkinson's Disease Rating Scale (UPDRS). There was a high degree...
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| Published in | Neurology Vol. 43; no. 5; p. 1040 |
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| Main Authors | , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
01.05.1993
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| Subjects | |
| Online Access | Get more information |
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| Abstract | We studied 10 regular exercising men with Parkinson's disease on levodopa (LD) under two conditions--no exercise and vigorous exercise started 1 hour after LD ingestion. We compared LD levels and motor scores on the Unified Parkinson's Disease Rating Scale (UPDRS). There was a high degree of agreement between plasma LD level and the patients' UPDRS scores 30 minutes later (mean Eta2 = 0.84) in both conditions, with no difference between the two. We conclude that LD levels accurately reflect UPDRS motor function in these patients, and that vigorous exercise started 1 hour after LD ingestion does not influence LD or motor scores. |
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| AbstractList | We studied 10 regular exercising men with Parkinson's disease on levodopa (LD) under two conditions--no exercise and vigorous exercise started 1 hour after LD ingestion. We compared LD levels and motor scores on the Unified Parkinson's Disease Rating Scale (UPDRS). There was a high degree of agreement between plasma LD level and the patients' UPDRS scores 30 minutes later (mean Eta2 = 0.84) in both conditions, with no difference between the two. We conclude that LD levels accurately reflect UPDRS motor function in these patients, and that vigorous exercise started 1 hour after LD ingestion does not influence LD or motor scores. |
| Author | Stebbins, G T Goetz, C G Carvey, P M Thelen, J A Bartley, E A MacLeod, C M |
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| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/8492923$$D View this record in MEDLINE/PubMed |
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| Snippet | We studied 10 regular exercising men with Parkinson's disease on levodopa (LD) under two conditions--no exercise and vigorous exercise started 1 hour after LD... |
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| SubjectTerms | Aged Exercise Humans Levodopa - blood Levodopa - therapeutic use Male Middle Aged Parkinson Disease - blood Parkinson Disease - drug therapy Parkinson Disease - physiopathology Physical Exertion |
| Title | Blood levodopa levels and unified Parkinson's disease rating scale function: with and without exercise |
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