In-vivo uptake of topically applied fluoride by human dental enamel

• Published in: Archives of oral biology Vol. 25; no. 8; pp. 617 - 621
• Main Authors: Baijot-Stroobants, J., Vreven, J.
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 1980
• Subjects: Adult; Dental Enamel - metabolism; Dentifrices - metabolism; Dentistry; Fluorides, Topical - metabolism; Humans; Time Factors; Toothpastes - metabolism
• ISSN: 0003-9969; 1879-1506
• DOI: 10.1016/0003-9969(80)90077-1

In-vivo F determinations were carried out using a non-destructive physical technique based on prompt activation by proton bombardment. 74 sound incisors were submitted to 4 min topical applications of commercial gels and solutions containing fluoride. The F uptake was measured for many hours, days and weeks following fluoride application. The largest amounts of fluoride were acquired by the enamel 30 min after an amine fluoride solution application (4460 parts/10 6). Two acidulated phosphate fluoride (APF) gels gave a mean enrichment of 1774 and 3277 parts/10 6 respectively, whereas amine fluoride (AmF) and monofluorophosphate gels were less efficient (228 and 105 parts/10 6 of enrichment respectively). The superiority of AmF solution treatment was observed for many weeks after fluoride application; 6 weeks were needed to leach all the fluoride acquired by the enamel whereas with APF gels, the initial F level was recovered 2 weeks after the topical application.