Solid phase C1q microassay for the rapid detection of circulating immune complexes

A C1q solid phase microassay was designed for the rapid detection of circulating immune complexes. Its level of sensitivity is comparable to that of the Raji cell and greater than the C1q binding assay; furthermore, it is faster and low in cost. These conditions make it more practical and applicable...

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Bibliographic Details
Published inJournal of immunological methods Vol. 59; no. 2; p. 237
Main Authors Orozco, A, Contreras, C E, Sánchez, P, Meilijson, O, Bianco, N E
Format Journal Article
LanguageEnglish
Published Netherlands 1983
Subjects
Antibodies, Anti-Idiotypic
Antigen-Antibody Complex - analysis
Binding Sites, Antibody
Complement Activating Enzymes - metabolism
Complement C1q
Hepatitis, Viral, Human - immunology
Humans
Immunosorbent Techniques
Lupus Erythematosus, Systemic - immunology
Radioimmunoassay - methods
Reference Standards
Stomach Neoplasms - immunology
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Summary:A C1q solid phase microassay was designed for the rapid detection of circulating immune complexes. Its level of sensitivity is comparable to that of the Raji cell and greater than the C1q binding assay; furthermore, it is faster and low in cost. These conditions make it more practical and applicable in the clinical setting.
ISSN:0022-1759
DOI:10.1016/0022-1759(83)90036-4