Technical note: Antimicrobial action of glass-ionomer lining cement on S. sanguis and S. mutans

• Published in: Dental materials Vol. 5; no. 4; pp. 281 - 282
• Main Authors: Barkhordar, R.A., Kempler, D., Pelzner, R.R.B., Stark, M.M.
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.07.1989
• Subjects: Dental Cavity Lining; Dental Cements - pharmacology; Glass Ionomer Cements - pharmacology; Microbial Sensitivity Tests; Streptococcus mutans - drug effects; Streptococcus sanguis - drug effects
• ISSN: 0109-5641; 1879-0097
• DOI: 10.1016/0109-5641(89)90076-6

There are a number of glass-ionomer lining cements available to the profession. It is generally agreed that the glass-ionomer cements demonstrate reasonably good biocompatibility. The purpose of this study was to evaluate the antimicrobial activity of six glass-ionomer cements on S. sanguis and S. mutans. Forty-eight plates of TSA-SRBC (10%), each with 3.0-mm-diam. wells, were divided into two groups (1 and 2) of 24 each. Group 1 was inoculated with S. sanguis (10558) and Group 2 with S. mutans (6715-13 w.t.). Each well was filled with 4.0 mg of one of the following liners: Glassic (A), Shofu lining cement (B), GC lining cement (C), Ever Bond (D), Gingiva Sea (E), and Ketac Bond (F); the empty wells served as control. Plates were incubated under microaerophilic conditions at 37°C, and checked daily over seven days for inhibition zones. Average inhibition zones (mm) at 7 days were as follows: Group 1 − 1A = 10.00, 1B = 7.83, 1C = 18.50, 1D = 13.00, 1E = 8.67 and 1F = 9.33; Group 2–2A = 3.08, 2B = 10.25, 2C = 12.75, 2D = 15.58, 2E = 8.83, and 2F = 3.20. All control wells were 0.0. GC liner and Ever Bond showed significantly greater overall inhibition of microbial growth than did other tested liners (p < 0.5). A one-way ANOVA and SNK test showed that all tested liners were significantly more toxic toward S. sanguis than toward S. mutans (p < 0.05).