Non-specific cross-reacting antigen serum concentration in myeloid leukemias

Non-specific cross-reacting antigen (NCA) was assayed radioimmunologically in normal sera and sera obtained from patients with chronic and acute myeloid leukemias. Normal value for NCA concentration was 37.8 ng/ml with a standard deviation of 14.6. In patients with chronic myeloid leukemia NCA serum...

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Bibliographic Details
Published inClinica chimica acta Vol. 103; no. 1; pp. 23 - 31
Main Authors Frénoy, Nicole, Burtin, Pierre
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier B.V 11.04.1980
Subjects
Adolescent
Adult
Aged
Antigens - analysis
Child
Child, Preschool
Cross Reactions
Female
Humans
Leukemia, Myeloid - drug therapy
Leukemia, Myeloid - immunology
Male
Middle Aged
Radioimmunoassay
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Summary:Non-specific cross-reacting antigen (NCA) was assayed radioimmunologically in normal sera and sera obtained from patients with chronic and acute myeloid leukemias. Normal value for NCA concentration was 37.8 ng/ml with a standard deviation of 14.6. In patients with chronic myeloid leukemia NCA serum concentration was significantly increased, and a study with regard to the stage of the disease (acute phase, blastic crisis, remission) was made. Individual cases were studied longitudinally. Patients with acute myeloid leukemia had a lower value than normal. The influence of chemotherapy on NCA serum concentration and the interest of NCA assay for follow-up of the patients are discussed.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0009-8981
1873-3492
DOI:10.1016/0009-8981(80)90226-0