Use of a Pulmonary Artery Catheter in Patients With Cardiogenic Shock　― A Systematic Review and Meta-Analysis

• Published in: Circulation Reports Vol. 7; no. 8; pp. CR-25-0088 - 598
• Main Authors: Kondo, Toru, Nakashima, Takahiro, Yamamoto, Takeshi, Nakayama, Naoki, Hanada, Hiroyuki, Hashiba, Katsutaka, Kirigaya, Jin, Ishizu, Tomoko, Hosoya, Yumiko, Katasako-Yabumoto, Aya, Okazaki, Yusuke, Yamamoto, Masahiro, Sakamoto, Kazuo, Arai, Marina, Osawa, Takumi, Tanaka, Akihito, Matsuo, Kunihiro, Yamaguchi, Junichi, Mano, Toshiaki, Kojima, Sunao, Noguchi, Teruo, Tsujimoto, Yasushi, Kikuchi, Migaku, Funazaki, Toshikazu, Tahara, Yoshio, Nonogi, Hiroshi, Matoba, Tetsuya
• Format: Journal Article
• Language: English
• Published: Japan The Japanese Circulation Society 08.08.2025
• Subjects: Acute coronary syndrome; Cardiogenic shock; Heart failure; Jcs/Jrc Emergency Cardiovascular Care Systematic Review Series 2025; Prognosis; Pulmonary artery catheter; Heart failure; Prognosis; Acute coronary syndrome; Cardiogenic shock; Pulmonary artery catheter
• ISSN: 2434-0790; 2434-0790
• DOI: 10.1253/circrep.CR-25-0088

Background: A pulmonary artery catheter (PAC) provides detailed hemodynamic data, and managing a patient with cardiogenic shock (CS) using a PAC potentially improves patient outcomes. Therefore, in this systematic review and meta-analysis we aimed to evaluate whether a PAC is associated with better outcomes in patients with CS.Methods and Results: Studies comparing PAC and non-PAC management in patients with CS were identified from the PubMed, Web of Science, and CENTRAL databases. There were no randomized controlled trials (RCTs). Of the 19 studies that met the inclusion criteria, 12 without a critical risk of bias were analyzed. PAC use was associated with lower in-hospital mortality when evaluated as a dichotomous outcome. Similar trends were observed in the time-to-event analyses. Substantial heterogeneity was observed across the studies. Subgroup analysis revealed better outcomes with PAC in patients with CS related to heart failure, but not in those with acute coronary syndrome. Sensitivity analyses, which included studies with a critical risk of bias, showed consistent trends favoring PAC use for crude in-hospital mortality. The overall certainty of the evidence was very low because of inconsistencies and biases.Conclusions: The PAC-guided CS management was associated with better in-hospital mortality, particularly in patients with heart failure-related CS. However, RCTs that evaluated the efficacy of PAC use as a primary purpose were not included, necessitating further RCTs to confirm these findings.