TCT-176 Comparison of Imputed Placebo Versus Observed Ischemic Stroke Rates in the Watchman Trials Represents a Significant Reduction in Risk

Imputed Placebo versus Observed WATCHMAN Ischemic Stroke Rate per 100 Patient - Years Study Average CHADS2 Score WATCHMAN Patients Imputed Untreated Control Event Rate Observed WATCHMAN Ischemic Stroke Rate (95% CI) Relative Risk Reduction PROTECT AF 2.2 5.6 to 5.7 1.3 (0.9, 2.0) 77% (64%, 84%) CAP...

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Bibliographic Details
Published inJournal of the American College of Cardiology Vol. 64; no. 11; p. B52
Main Authors Hanzel, George, berman, aaron, Almany, Steven L, Huber, Kenneth, Kar, Saibal, Holmes, David
Format Journal Article
LanguageEnglish
Published New York Elsevier Inc 16.09.2014
Elsevier Limited
Subjects
Cardiology
Cardiovascular
Drug therapy
Internal Medicine
Stroke
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Summary:Imputed Placebo versus Observed WATCHMAN Ischemic Stroke Rate per 100 Patient - Years Study Average CHADS2 Score WATCHMAN Patients Imputed Untreated Control Event Rate Observed WATCHMAN Ischemic Stroke Rate (95% CI) Relative Risk Reduction PROTECT AF 2.2 5.6 to 5.7 1.3 (0.9, 2.0) 77% (64%, 84%) CAP 2.5 6.4 1.1 (0.8, 1.7) 83% (73%, 88%) PREVAIL 2.6 6.6 to 6.7 2.5 (1.5, 4.3) 62% (35%, 77%)
ISSN:0735-1097
1558-3597
DOI:10.1016/j.jacc.2014.07.215