Glucopyranosyl Lipid a (GLA) a Toll-like Receptor 4 (TLR4) Agonist for Use As an Adjuvant in Combination with Peanut Allergen Immunotherapy

PBMC from peanut allergic individuals were labeled with CellTrace Dye, incubated with PE and GLA (30μg/ml-3ng/ml) and CD4+T cell proliferation was measured by FACS.

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Bibliographic Details
Published inJournal of allergy and clinical immunology Vol. 137; no. 2; p. AB129
Main Authors Soos, Timothy J, Li, Li, Graver, Keith, Schiding, Joanne, Xenos, Adrienne, Chen, Dongling, Fitch, Neil, Haddad, El-Bdaoui, Jones, Catherine, Arendt, Christopher
Format Journal Article
LanguageEnglish
Published St. Louis Elsevier Inc 01.02.2016
Elsevier Limited
Subjects
Allergy and Immunology
Cell growth
Food allergies
Immunotherapy
Rodents
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Summary:PBMC from peanut allergic individuals were labeled with CellTrace Dye, incubated with PE and GLA (30μg/ml-3ng/ml) and CD4+T cell proliferation was measured by FACS.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2015.12.555