Regulation of IL-4 Gene Expression By SIRT1 in Human Mast Cell

Rationale Histone protein modification control gene transcription via chromatin remodeling. Because a differentiation from naïve T cell to Th2 cell was induced by the chromatin remodeling, it may regulate allergic diseases.

Saved in:
Bibliographic Details
Published inJournal of allergy and clinical immunology Vol. 137; no. 2; p. AB75
Main Authors Nakamaru, Yuji, Takagi, Dai, Fukuda, Satoshi
Format Journal Article
LanguageEnglish
Published St. Louis Elsevier Inc 01.02.2016
Elsevier Limited
Subjects
Allergy and Immunology
Gene expression
Online AccessGet full text

Cover

More Information
Summary:Rationale Histone protein modification control gene transcription via chromatin remodeling. Because a differentiation from naïve T cell to Th2 cell was induced by the chromatin remodeling, it may regulate allergic diseases.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2015.12.254