Serum Interleukin-7 (IL-7) Level May Be a Marker of T-Cell Homeostasis in Partial DiGeorge Syndrome (pDGS)

Blood samples of consecutive pDGS children with chromosome 22q11.2 deletion (median age: 45 months, range: 1-231 months) were analyzed for lymphocyte phenotypes by flow cytometry (n = 27), T cell receptor excision circles (TRECs) by real time PCR (n = 24) and IL-7 levels by ELISA (n = 19).

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Bibliographic Details
Published inJournal of allergy and clinical immunology Vol. 123; no. 2; p. S86
Main Authors Tantibhaedhyangkul, U, Davis, C.M, Noroski, L.M, Hanson, I.C, Shearer, W.T, Chinen, J
Format Journal Article
LanguageEnglish
Published St. Louis Mosby, Inc 01.02.2009
Elsevier Limited
Subjects
Allergy and Immunology
Homeostasis
Immune system
T cell receptors
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Summary:Blood samples of consecutive pDGS children with chromosome 22q11.2 deletion (median age: 45 months, range: 1-231 months) were analyzed for lymphocyte phenotypes by flow cytometry (n = 27), T cell receptor excision circles (TRECs) by real time PCR (n = 24) and IL-7 levels by ELISA (n = 19).
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2008.12.302