Association of hand-grip strength and non-alcoholic fatty liver disease index in older adults
This study examined the association of hand-grip strength (HGS) and non-alcoholic fatty liver disease (NAFLD) index in older adults. This was a cross-sectional study involving 538 older adults with mean age of 74.3±6.4 years. Body composition parameters including height, percent body fat, body mass...
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Published in | Journal of exercise nutrition & biochemistry Vol. 22; no. 4; pp. 62 - 68 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
Korea (South)
한국운동영양학회
31.12.2018
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Subjects | |
Online Access | Get full text |
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Summary: | This study examined the association of hand-grip strength (HGS) and non-alcoholic fatty liver disease (NAFLD) index in older adults.
This was a cross-sectional study involving 538 older adults with mean age of 74.3±6.4 years. Body composition parameters including height, percent body fat, body mass index (BMI), waist circumference (WC), was determined using body composition analyzer. HGS was assessed using a dynamometer, and NAFLD was diagnosed by the simple NAFLD score (SNS), hepatic steatosis index (HSI), NAFLD fibrosis score (NFS), and fibrosis 4 calculator (FIB-4). Based on relative HGS, subjects were classified as High HGS, Mid HGS, and Low HGS group. Based on SNS, HSI, NFS and FIB-4 score, subjects were classified as High risk and Low risk group. Logistic regression analyses were used to determine the odds ratio (OR) and 95% confidence interval (CI) of HGS levels for having steatosis and fibrosis.
There were linear decreases in NAFLD index such as SNS (P<.001), HSI (P<.001), NFS (P=.001), and FIB-4 (P=.041) across incremental HGS levels. Compared to the High HGS group (reference), the Low HGS group had significantly higher ORs of having SNS (OR=4.583, 95% CI=2.608-8.054, P<.001), HSI (OR=11.697, 95% CI=5.261-26.005, P<.001), and NFS (OR=1.709, 95% CI=1.005-2.907, P=.048).
The current findings suggest that a lifestyle intervention consisting of a normal weight and physical fitness should be promoted as a preventive means against NAFLD associated with HGS. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 2233-6834 2233-6842 2233-6842 |
DOI: | 10.20463/jenb.2018.0031 |