Iodine-induced thyrotoxicosis in a patient treated with glue and lipiodised oil for pelvic congestion syndrome

On examination the patient was generally unwell; her blood pressure was 132/70 mm Hg, her pulse was 97 beats per min, and her BMI was 20·7 kg/m2. 123Iodine thyroid scintigraphy showed no significant uptake with a blunted measured value of 0·4% at 120 min (average value 12% at 120 min for a mean TSH...

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Published inThe Lancet (British edition) Vol. 403; no. 10445; pp. 2732 - 2733
Main Authors Schubert, Louis, Barat, Maxime, Bonnet-Serrano, Fidéline, Bravetti, Marine, Clerc, Jérôme, Groussin, Lionel, Bouys, Lucas
Format Journal Article
LanguageEnglish
Published England Elsevier Ltd 22.06.2024
Elsevier Limited
Subjects
Adhesives - adverse effects
Adult
Amiodarone
Appendix
Blood pressure
Computed tomography
Ethiodized Oil - adverse effects
Female
Humans
Hyperthyroidism
Iodine
Iodine - adverse effects
Medical imaging
Ovaries
Pelvic Pain - etiology
Scintigraphy
Thyroid
Thyroid gland
Thyroid-stimulating hormone
Thyrotoxicosis
Thyrotoxicosis - chemically induced
Varicose veins
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Summary:On examination the patient was generally unwell; her blood pressure was 132/70 mm Hg, her pulse was 97 beats per min, and her BMI was 20·7 kg/m2. 123Iodine thyroid scintigraphy showed no significant uptake with a blunted measured value of 0·4% at 120 min (average value 12% at 120 min for a mean TSH of 1·2 mIU/L in France; appendix). Interestingly, a study proposed a cutoff level of 117 HU for the density of the thyroid seen on unenhanced CT scan to distinguish patients with amiodarone-induced hyperthyroidism from healthy controls and from euthyroid amiodarone-treated patients (appendix).
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
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ISSN:0140-6736
1474-547X
1474-547X
DOI:10.1016/S0140-6736(24)01135-8