Magnesium hydrogen carbonate natural mineral water enriched with K(+)-citrate and vitamin B6 improves urinary abnormalities in patients with calcium oxalate nephrolithiasis

• Published in: Urologia internationalis Vol. 60; no. 2; p. 105
• Main Authors: Bren, A, Kmetec, A, Kveder, R, Kaplan-Pavlovcic, S
• Format: Journal Article
• Language: English
• Published: Switzerland 1998
• Subjects: Adult; Calcium Oxalate - urine; Creatinine - urine; Female; Follow-Up Studies; Humans; Hydrogen-Ion Concentration; Magnesium - therapeutic use; Male; Middle Aged; Mineral Waters - therapeutic use; Potassium Citrate - therapeutic use; Prospective Studies; Pyridoxine - therapeutic use; Recurrence; Treatment Outcome; Urinary Calculi - therapy; Urinary Calculi - urine; Urination Disorders - etiology; Urination Disorders - therapy
• ISSN: 0042-1138
• DOI: 10.1159/000030221

The influence of drinking magnesium hydrogen carbonate natural mineral water enriched with potassium citrate on urinary metabolic abnormalities was prospectively studied in 27 patients with recurrent calcium oxalate nephrolithiasis. The mean 24-hour urinary pH shifted from 6.34 to 6.93 (p < 0.01), the mean urinary magnesium/urinary creatinine ratio rose from 0.47 to 0.67 (p < 0.01), the mean urinary citrate/urinary creatinine ratio increased from 0.26 to 0.35 (p NS), and the mean 24-hour urinary calcium decreased from 7.98 to 6.05 mmol (p < 0.05). The effects of magnesium hydrogen carbonate natural mineral water enriched with potassium citrate were found to be favorable on urinary calcium, urinary magnesium/urinary creatinine ratio and urinary pH in patients with calcium oxalate nephrolithiasis.