Microvascular Imaging Using Swept-Source Optical Coherence Tomography with Single-Channel Acquisition

This study proposes a new approach to improve the phase stability for swept-source optical coherence tomography (SS-OCT) with single-channel acquisition. This approach can improve the phase instability due to the A-scan trigger jitter from the swept source, or the asynchronization between the A-scan...

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Bibliographic Details
Published inApplied physics express Vol. 4; no. 9; pp. 097001 - 097001-3
Main Authors Tsai, Meng-Tsan, Chi, Ting-Ta, Liu, Hao-Li, Chang, Feng-Yu, Yang, Chih-Hsun, Lee, Cheng-Kuang, Yang, Chih-Chung
Format Journal Article
LanguageEnglish
Published The Japan Society of Applied Physics 01.09.2011
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Summary:This study proposes a new approach to improve the phase stability for swept-source optical coherence tomography (SS-OCT) with single-channel acquisition. This approach can improve the phase instability due to the A-scan trigger jitter from the swept source, or the asynchronization between the A-scan trigger and high-speed digitizer, which enables the visualization of vascular structures by SS-OCT. Aside from reducing the phase noise of the OCT system, only one channel is required for the A-scan trigger, data storage, and wavelength calibration by implementing the proposed approach. Finally, human skin was scanned in vivo to demonstrate the vascular images.
Bibliography:Schematic diagram of the SS-OCT system with the single-channel acquisition. FC: fiber coupler; PC: polarization controller; FBG: fiber Bragg grating; CIR: circulator. (a) Interfered spectrum combined with a trigger signal from a narrowband FBG. (b) Measured sensitivity at different depths. Probability distribution of phase error measured from a glass slide of 250 μm thickness over 1000 A-scans by using the different acquisition approaches, including: (a) conventional two-channel acquisition and (b) single-channel acquisition. (a) In vivo two-dimensional OCT image obtained from human fingertip; (b) vascular image obtained from (a) by the OMAG method; and (c) phase difference between adjacent A-scans of (b). The white arrow indicates the sweat gland duct and the blue arrows represent the vessels. The scale bar is 1 mm in length.
ISSN:1882-0778
1882-0786
DOI:10.1143/APEX.4.097001