Patterns of brain metastasis in lung cancer

Brain metastasis as the only site of spread in lung cancer was studied. Ninety-two (13.1%) of 701 lung cancer patients had brain metastasis at the time of diagnosis. Eighteen and 16 patients had small primary lesion and were N0-1 disease, respectively. Thirty-two patients had sole brain metastasis....

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Bibliographic Details
Published inOncology reports Vol. 8; no. 4; p. 781
Main Authors Satoh, H, Ishikawa, H, Yamashita, Y T, Kurishima, K, Ohtsuka, M, Sekizawa, K
Format Journal Article
LanguageEnglish
Published Greece 01.07.2001
Subjects
Adenocarcinoma - secondary
Adenocarcinoma - surgery
Adult
Aged
Aged, 80 and over
Brain Neoplasms - secondary
Brain Neoplasms - surgery
Carcinoma, Large Cell - secondary
Carcinoma, Large Cell - surgery
Carcinoma, Small Cell - secondary
Carcinoma, Small Cell - surgery
Carcinoma, Squamous Cell - secondary
Carcinoma, Squamous Cell - surgery
Female
Humans
Lung Neoplasms - pathology
Lung Neoplasms - surgery
Male
Middle Aged
Retrospective Studies
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Summary:Brain metastasis as the only site of spread in lung cancer was studied. Ninety-two (13.1%) of 701 lung cancer patients had brain metastasis at the time of diagnosis. Eighteen and 16 patients had small primary lesion and were N0-1 disease, respectively. Thirty-two patients had sole brain metastasis. Patients with sole brain metastasis had more favorable survival than patients with other metastatic sites (p=0.0165). Brain metastasis may occur even with small primary lesion and/or without regional lymph node involvement. Well-planned surgery or stereotactic radiosurgery will result in enhanced survival.
ISSN:1021-335X
1791-2431
DOI:10.3892/or.8.4.781