Bimodal distributions of highest ethanol acceptance concentrations in two strains of rats

Two groups of non-deprived male Wistar rats and one group of male Sprague-Dawley rats were offered a choice of water an daily-increasing concentrations of ethanol. Each group's distribution of highest ethanol acceptance concentrations approximated a bimodal distribution with respect to concentr...

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Bibliographic Details
Published inPharmacology, biochemistry and behavior Vol. 8; no. 6; pp. 695 - 699
Main Authors Goas, J.Allen, Lippa, Arnold S.
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.06.1978
Subjects
Alcohol Drinking
Animals
Bimodal distribution
Dose-Response Relationship, Drug
Drinking Behavior - physiology
Ethanol acceptance
Ethanol rejection
Male
Rats
Rats, Inbred Strains
Species Specificity
Sprague-Dawley
Wistar
Sprague-Dawley
Ethanol acceptance
Bimodal distribution
Ethanol rejection
Wistar
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Summary:Two groups of non-deprived male Wistar rats and one group of male Sprague-Dawley rats were offered a choice of water an daily-increasing concentrations of ethanol. Each group's distribution of highest ethanol acceptance concentrations approximated a bimodal distribution with respect to concentration. Further, rats in each group which drank ethanol at high concentrations maintained relatively constant intakes of pure ethanol. These results are discussed in terms of taste and olfaction, central nervous system sensitivity and emotionality.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0091-3057
1873-5177
DOI:10.1016/0091-3057(78)90268-X