Enantiospecific CH Activation Using Ruthenium Nanocatalysts

• Published in: Angewandte Chemie Vol. 127; no. 36; pp. 10620 - 10623
• Main Authors: Taglang, Céline, Martínez-Prieto, Luis Miguel, del Rosal, Iker, Maron, Laurent, Poteau, Romuald, Philippot, Karine, Chaudret, Bruno, Perato, Serge, Sam Lone, Anaïs, Puente, Céline, Dugave, Christophe, Rousseau, Bernard, Pieters, Grégory
• Format: Journal Article
• Language: English; German
• Published: Weinheim WILEY-VCH Verlag 01.09.2015; WILEY‐VCH Verlag
• Subjects: Ab-initio-Rechnungen; Activation; C-H-Aktivierung; Deuterium; Isotopenmarkierung; Nanoparticles; Nanopartikel; Nanostructure; Ruthenium; Selectivity; Strategy

The activation of CH bonds has revolutionized modern synthetic chemistry. However, no general strategy for enantiospecific CH activation has been developed to date. We herein report an enantiospecific CH activation reaction followed by deuterium incorporation at stereogenic centers. Mechanistic s...