Neurotropic, anti-inflammatory and antitumor properties of hopantenic acid: a chemoinformatic analysis of its molecule

Hopantenic acid is a well-known nootropic drug similar in its chemical structure to pantothenic acid (vitamin B5). Neurotropic effects of hopantenic acid act through binding with delta- and kappa opioid receptors, modulation of acetylcholine secretion and relationship with dopamine receptors. Beside...

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Published inZhurnal nevrologii i psikhiatrii imeni S.S. Korsakova Vol. 115; no. 5 Pt 2; p. 61
Main Authors Gromova, O A, Troshin, I Yu, Limanova, O A, Gromov, A N, Fedotova, L E, Rudakov, K V
Format Journal Article
LanguageRussian
Published Russia (Federation) 2015
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Summary:Hopantenic acid is a well-known nootropic drug similar in its chemical structure to pantothenic acid (vitamin B5). Neurotropic effects of hopantenic acid act through binding with delta- and kappa opioid receptors, modulation of acetylcholine secretion and relationship with dopamine receptors. Besides neurotropic effects, hopantenic acid may modulate the metabolism of prostaglandins, steroids and have antitumor effects.
ISSN:1997-7298
DOI:10.17116/jnevro20151155261-71