Steroidal Components from the Roots and Rhizomes of Smilacina henryi and Their Cytotoxic Activities

Nine steroidal components, including a new pregnane glycoside (1), were obtained from the roots and rhizomes of Smilacina henryi. Their structures were determined via extensive spectroscopic data including, IR, HRESIMS and 1D, 2D NMR data analysis. Furthermore, their cytotoxic activities against hum...

Full description

Saved in:
Bibliographic Details
Published inRecords of natural products Vol. 14; no. 3; pp. 225 - 230
Main Authors Chen, Zhenlin, Xue, Xuanji, Zhang, Shuo, Zhang, Rongxin, Zhang, Xiulei, Guo, Zengjun, Zhang, Xin
Format Journal Article
LanguageEnglish
Published Gebze ACG Publications 01.05.2020
Subjects
Cytotoxicity
Online AccessGet full text

Cover

More Information
Summary:Nine steroidal components, including a new pregnane glycoside (1), were obtained from the roots and rhizomes of Smilacina henryi. Their structures were determined via extensive spectroscopic data including, IR, HRESIMS and 1D, 2D NMR data analysis. Furthermore, their cytotoxic activities against human HepG2 and SW620 tumor cells were evaluated by the MTT method and compounds 2, 3, 5, 8 and 9 showed moderate activity with IC50 values raging from 18.4 to 86.3 μM.
ISSN:1307-6167
1307-6167
DOI:10.25135/rnp.156.1908.1390