DSC analysis of human fat tissue in idiopathic avascular necrosis of the femoral head A preliminary study

• Published in: Journal of thermal analysis and calorimetry Vol. 95; no. 3; pp. 781 - 785
• Main Authors: Pintér, Cs, Bognár, G., Horváth, B., Sydo, T., Ligeti, E., Pulai, J., Lőrinczy, D.
• Format: Journal Article Conference Proceeding
• Language: English
• Published: Dordrecht Springer Netherlands 01.03.2009; Springer
• Subjects: Analytical Chemistry; Biological and medical sciences; Chemistry; Chemistry and Materials Science; Inorganic Chemistry; Investigative techniques, diagnostic techniques (general aspects); Measurement Science and Instrumentation; Medical Aspects; Medical sciences; Osteoarticular system. Muscles; Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques; Physical Chemistry; Polymer Sciences; osteonecrosis; fatty acids; DSC; gas chromatography; Human; Differential scanning calorimetry; Gas chromatography; Femoral head; Diseases of the osteoarticular system; Osteonecrosis; Thermal analysis; Oils and fats; Fatty acids; Necrosis
• ISSN: 1388-6150; 1588-2926; 1572-8943
• DOI: 10.1007/s10973-008-9470-8

Avascular necrosis of human femoral head (ANFH) causes incongruity in the joint that leads to disability in patients requires total hip arthroplasty (THA). Several etiological factors of ANFH have been proposed in the literature but there are cases of idiopathic origin. We observed macroscopic variation in quality of the subcutaneous fat tissue in patients with ANFH compared to patients with osteoarthritis or hip fracture during THA procedures. The samples were analysed by histology, gas chromatography (GC) and differential scanning calorimetry (DSC). Conclusion: the alteration in the fatty acid profile did not cause histological changes, however we could detect biochemical changes using DSC and GC.