Directional Cell Migration Guide for Improved Tissue Regeneration

The field of tissue regeneration has seen a paradigm shift after one wave of technological innovation after another, which has notably made significant contributions to basic cellular response control and overall tissue regeneration. One particular area that is seeing rekindled interest after techno...

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Bibliographic Details
Published inAdvances in experimental medicine and biology Vol. 1249; p. 131
Main Authors Shin, Young Min, Yang, Hee Seok, Chun, Heung Jae
Format Journal Article
LanguageEnglish
Published United States 2020
Subjects
Cell Movement
Humans
Regeneration
Tissue Engineering
Electrospinning
Radially aligned
Patterning
Topographical cue
Cell migration
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Summary:The field of tissue regeneration has seen a paradigm shift after one wave of technological innovation after another, which has notably made significant contributions to basic cellular response control and overall tissue regeneration. One particular area that is seeing rekindled interest after technological innovation is managing cell migration toward defects because successful host cell migration from adjacent tissue can accelerate overall regeneration time in tissue defects that are either large in size or irregular in shape. This chapter surveys significant advances on directed cell migration upon topological cues. First, we introduce several examples of patterning and electrospinning technology for guiding directed cell migration, followed by a discussion on approaches to influencing radially aligned topography in pattern or electrospun sheet for overall tissue regeneration.
ISSN:0065-2598
DOI:10.1007/978-981-15-3258-0_9