Self-Assembled Synthesis and Characterization of Novel [Co(1-vinylimidazole)6].NO3 Polymer: Highly Efficient Antimicrobial Agent

• Published in: Journal of the Chemical Society of Pakistan Vol. 43; no. 6; p. 706
• Main Authors: Fouzia Chang, Fouzia Chang, Najma Memon, Najma Memon, Shahabuddin Memon, Shahabuddin Memon, Ayaz Ali Memon, Ayaz Ali Memon, Saddam Hussain Bughio, Saddam Hussain Bughio, Muhammad Nawaz Tahir and Abdul Sattar Chang, Muhammad Nawaz Tahir and Abdul Sattar Chang
• Format: Journal Article
• Language: English
• Published: Knowledge Bylanes 31.12.2021
• Subjects: Hydrogen; Magnetism; Polymer industry; Polymers; Niger
• ISSN: 0253-5106
• DOI: 10.52568/000973/JCSP/43.06.2021

Cobalt coordination polymer i.e. [Co(1-VI)6]and#183;NO3 was successfully synthesized with cobalt metal and (VI = vinylimidazole) and characterized by elemental analysis, FTIR, UV/Vis spectroscopy and X-ray crystallography. The structure of the compound was determined by single X-ray crystallography at temperature 296 K with a Bruker APEX II CCD diffractometer using Mo-Kα radiations (λ = 0.71073 and#197;), R = 0.0642 and 0.0989. Orthorhombic unit cell parameters are a = 16.1341 (6) and#197;, b = 16.5179(16) and#197;, c = 18.2664(16) and#197;, V= 4868.0 (8) and#197;, Dx = 4, Mr = 937.91. The X-ray crystallography studies showed that the compound is polymeric in nature, in which cobalt atom coordinated with six N atoms of the 1-vinylimidazole ligands in a distorted orthorhombic geometry. As-prepared compound was screened in vitro against a variety of microorganisms, such as Gram-positive (G +ve) Staphylococcusaureus (S. aureus) and Gram-negative (G -ve) Escherichia coli (E. coli) bacterial strains, and fungal species with Aspergillus niger (A. niger) and Rhizopus stolonifer(R.stolonifer)by applying disk diffusion method. MIC (minimum inhibitory concentration) value for prepared [Co(1-VI)6]and#183;NO3 compound is 125 μg.mL-1a this MIC value cobalt polymer showed higher activity against E. coli and S. aureus () as compared to fungi including; R. StoloniferandA. Niger at 125 μg.mL-1).This study helps to reduce the risk of infectious diseases caused by various microorganisms.