A New β-Ionone from Liriodendron tulipifera

A new β -ionone, litulipiferic acid ( 12 ), was isolated from the leaves of Liriodendron tulipifera (Magnoliaceae). The structure of the new β -ionone was elucidated by chemical and physical evidence. The anticancer effect of compounds 1–3 , 5 , 6 , and 8 on A375 cells exhibit a dose-dependent behav...

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Published inChemistry of natural compounds Vol. 58; no. 3; pp. 455 - 458
Main Authors Chen, C. Y., Liu, C. M., Yeh, H. C., Li, W. J., Li, H. T., Cheng, M. J., Hsieh, P. C., Wang, H. M.
Format Journal Article
LanguageEnglish
Published New York Springer US 01.05.2022
Springer Nature
Springer Nature B.V
Subjects
Anticancer properties
Chemistry
Chemistry and Materials Science
Chemistry, Medicinal
Chemistry, Organic
Chemistry/Food Science
Life Sciences & Biomedicine
Organic Chemistry
Pharmacology & Pharmacy
Physical Sciences
Plant Sciences
Science & Technology
epitulipinolide diepoxide
ionone
Magnoliaceae
Liriodendron tulipifera
beta-ionone
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Summary:A new β -ionone, litulipiferic acid ( 12 ), was isolated from the leaves of Liriodendron tulipifera (Magnoliaceae). The structure of the new β -ionone was elucidated by chemical and physical evidence. The anticancer effect of compounds 1–3 , 5 , 6 , and 8 on A375 cells exhibit a dose-dependent behavior. When cells were exposed to epitulipinolide diepoxide ( 8 ) at 100 μM, the data exhibited viabilities of less than 25% after 24 h of treatment.
ISSN:0009-3130
1573-8388
DOI:10.1007/s10600-022-03708-8