Lectin-binding patterns in the development of the cerebellum

We studied the binding distribution of several lectins, Con A, DBA, UEA and WGA, in the embryonic development of the chick cerebellum between stages 18 to 45 of Hamburger and Hamilton. We observed a differential labeling (in intensity and distribution) in the migratory and cortical layers of the cer...

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Bibliographic Details
Published inAnatomy and embryology Vol. 189; no. 2; p. 169
Main Authors Viejo Tirado, F, Peña Melián, A, Puerta Fonollá, J
Format Journal Article
LanguageEnglish
Published Germany 01.02.1994
Subjects
Animals
Cerebellum - chemistry
Cerebellum - embryology
Cerebellum - metabolism
Chick Embryo
Concanavalin A - analysis
Embryonic and Fetal Development
Extracellular Matrix - chemistry
Glycoproteins - analysis
Glycosaminoglycans - analysis
Lectins - analysis
Lectins - metabolism
Plant Lectins
Protein Binding
Wheat Germ Agglutinins - analysis
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Summary:We studied the binding distribution of several lectins, Con A, DBA, UEA and WGA, in the embryonic development of the chick cerebellum between stages 18 to 45 of Hamburger and Hamilton. We observed a differential labeling (in intensity and distribution) in the migratory and cortical layers of the cerebellum anlage with these different lectins. The different distributions and modifications in the labeling pattern suggest intense variations of the glycoproteins and glycosaminoglycans in the extracellular matrix during development. These variations coincide with cellular and organizational phenomena in the migratory and cortical layers, and suggest compartmentalization of the Purkinje cell labeling.
ISSN:0340-2061
DOI:10.1007/BF00185775