Histology of the bone marrow antibody response. An immunocytochemical study during the secondary response in mouse and rat

• Published in: Virchows Archiv. B, Cell pathology Vol. 44; no. 1; p. 65
• Main Authors: Geldof, A A, Rimmelzwaan, G F, Langevoort, H L
• Format: Journal Article
• Language: English
• Published: Germany 1983
• Subjects: Animals; Antibody Formation; Bone Marrow - analysis; Bone Marrow - immunology; Bone Marrow - ultrastructure; Cytoplasm - immunology; Female; Histocytochemistry; Horseradish Peroxidase - immunology; Immunoglobulins - analysis; Injections, Intravenous; Injections, Subcutaneous; Mice; Rats

The histology of the specific and non-specific antibody response in mouse and rat bone marrow was studied after subcutaneous priming and intravenous boosting with horseradish peroxidase (HRP). Cells producing specific antibody against HRP were found only occasionally in the bone marrow after subcuta...