Studies on 2-Substituted Thiazolines. L. Reaction with Cyanoacetic Acid

2-Substituted thiazokines (IIa-d) were prepared from 2-thiothiazokidone. IIa-d were converted to 2-(ethoxycarbonylcyanomethylene) thiazolidine (III) and its N-acetate and N-methyl derivative. Thiolester analogs of III were obtained by the reaction of IIa-d and cyanoacetic acid in acetic anhydride.

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Bibliographic Details
Published in	Chemical & pharmaceutical bulletin Vol. 21; no. 7; pp. 1426 - 1430
Main Authors	SAKURAI, YOZIRO, KURUMI, MASATERU, OKUTOME, TOSHIYUKI, SATO, SHIGEO, YAMAGUCHI, KAZUTAKA
Format	Journal Article
Language	English
Published	Tokyo The Pharmaceutical Society of Japan 1973 Japan Science and Technology Agency
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Summary:	2-Substituted thiazokines (IIa-d) were prepared from 2-thiothiazokidone. IIa-d were converted to 2-(ethoxycarbonylcyanomethylene) thiazolidine (III) and its N-acetate and N-methyl derivative. Thiolester analogs of III were obtained by the reaction of IIa-d and cyanoacetic acid in acetic anhydride.
ISSN:	0009-2363 1347-5223
DOI:	10.1248/cpb.21.1426