Association of inflammation, dyslipidemia, obesity and physical activity status in children

• Published in: Motriz : Revista de Educação Física. Unesp Vol. 22; no. 2; pp. 18 - 26
• Main Authors: Guedes, Juliano Magalhães, Mamêde Neto, José Bontempo, Andaki, Alynne Christian Ribeiro, Pereira, Patrícia Feliciano, Oliveira, Michelle Dias de, Dias, Roberto Sousa, Paula, Sérgio Oliveira de, Natali, Antônio José, Rogério, Alexandre de Paula, Mendes, Edmar Lacerda
• Format: Journal Article
• Language: English
• Published: Universidade Estadual Paulista 01.06.2016; Universidade Estadual Paulista (UNESP)
• Subjects: child; inflammatory biomarkers; obesity; physical activity status; SPORT SCIENCES; inflammatory biomarkers; physical activity status; obesity; child
• ISSN: 1980-6574; 1980-6574
• DOI: 10.1590/S1980-6574201600020003

Abstract The aim of this study was to verify the association between inflammatory biomarkers, dyslipidemia, obesity and physical activity status in 10-years old children. Ninety-four children participated in this study and were classified into eutrophic (n=36), overweight (n=34) or obese (n=24) according to their body mass index (BMI). The genic expression of interleukin 6 (IL-6), tumor necrosis factor alpha (TNF-α) and chemokine C-C motif ligand 2 (CCL-2) mRNA; the serum concentration of high-density lipoprotein cholesterol (HDL-c) and triglycerides; BMI, percentage of body fat (% BF) and waist circumference; and the number of steps per day were determined. The expression of IL-6, TNF-α and CCL-2 were associated (p < 0.05) positively with serum triglycerides, BMI, % BF and waist circumference, and negatively with serum HDL-c. No association (p > 0.05) between pro-inflammatory biomarkers and number of steps per day was found.