Rare Presentation of Prostate Cancer Mimicking Malignant Lymphoma with Generalized Lymphadenopathy

Abstract Prostate cancer typically metastasizes to bones and regional lymph nodes. Generalized lymphadenopathy is a rare manifestation of metastatic prostate cancer. We report a case of prostate cancer in a 65-year-old male with initial presentation of generalized lymphadenopathy and no urinary symp...

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Bibliographic Details
Published inJournal of cancer research and practice Vol. 1; no. 1; pp. 70 - 74
Main Authors Tsai, Yu-Fen, Cho, Shih-Feng, Wu, Chun-Chieh, Liu, Ta-Chih
Format Journal Article
LanguageEnglish
Published Elsevier B.V 01.06.2014
Wolters Kluwer Medknow Publications
Subjects
generalized lymphadenopathy
Hematology, Oncology and Palliative Medicine
malignant lymphoma
prostate cancer
generalized lymphadenopathy
malignant lymphoma
prostate cancer
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Summary:Abstract Prostate cancer typically metastasizes to bones and regional lymph nodes. Generalized lymphadenopathy is a rare manifestation of metastatic prostate cancer. We report a case of prostate cancer in a 65-year-old male with initial presentation of generalized lymphadenopathy and no urinary symptoms. Lymph node biopsy revealed metastatic adenocarcinoma, and immunohistochemical staining was positive for prostate-specific antigen (PSA) compatible with a prostatic origin. Directed biopsy confirmed that the tumor originated in the prostate. Therefore, the prostate should be considered a possible origin of metastatic adenocarcinoma in men, and presentations consistent with generalized lymphadenopathy cannot exclude a diagnosis of prostate cancer.
ISSN:2311-3006
2311-3006
DOI:10.1016/S2311-3006(16)30027-1