4-hydroxy-2-quinolones. 201. Synthesis, structure, and diuretic activity of hydroxy- and alkoxy- anilides of 6-hydroxy-2-methyl-4-oxo-2,4-dihydro- 1H-pyrrolo[3,2,1-ij]quinoline-5-carboxylic acid

Hydroxy- and alkoxyanilides of 6-hydroxy-2-methyl-4-oxo-2,4-dihydro-1 H -pyrrolo[3,2,1- ij ]quinoline-5-carboxylic acids have been synthesized as potential diuretic agents. Features of their purification, their steric structure, and biological activity are discussed.

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Bibliographic Details
Published inChemistry of heterocyclic compounds (New York, N.Y. 1965) Vol. 47; no. 9; pp. 1122 - 1127
Main Authors Ukrainets, I. V., Golik, N. Yu, Shemchuk, A. L., Kravchenko, V. N.
Format Journal Article
LanguageEnglish
Published Boston Springer US 01.12.2011
Springer
Subjects
Alkaloids
Chemistry
Chemistry and Materials Science
Diuretics
Methylation
Organic acids
Organic Chemistry
Pharmacy
Quinoline
amidation
X-ray structural analysis
4-hydroxy-2-oxoquinoline-3-carboxylic acids
diuretic activity
anilides
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Summary:Hydroxy- and alkoxyanilides of 6-hydroxy-2-methyl-4-oxo-2,4-dihydro-1 H -pyrrolo[3,2,1- ij ]quinoline-5-carboxylic acids have been synthesized as potential diuretic agents. Features of their purification, their steric structure, and biological activity are discussed.
ISSN:0009-3122
1573-8353
DOI:10.1007/s10593-011-0882-1