GETools: gene expression tool for analysis of transcriptome experiments in E. coli

Microarray methods provide global evaluation of changes in gene expression that the cell uses to adapt to different conditions. Given the rich legacy of biological knowledge available for Escherichia coli, the analysis of microarray data poses the challenge of comparing them against the knowledge av...

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Bibliographic Details
Published inTrends in genetics Vol. 18; no. 4; pp. 217 - 218
Main Authors Huerta, Araceli M., Glasner, Jeremy D., Gutiérrez-Rı́os, Rosa Marı́a, Blattner, Fred R., Collado-Vides, Julio
Format Journal Article
LanguageEnglish
Published Oxford Elsevier Ltd 01.04.2002
Elsevier Science
Subjects
Bacteriology
Biological and medical sciences
expression profile
Fundamental and applied biological sciences. Psychology
gene regulation
Genetics
GETools
microarray
Microbiology
mRNA expression
transcriptome
GETools
Biotechnology
microarray
Techniques & Methods
gene regulation
transcriptome
Genetics
Bioinformatics
expression profile
mRNA expression
Gene
Escherichia coli
Bacteria
Software
Gene expression
Enterobacteriaceae
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Summary:Microarray methods provide global evaluation of changes in gene expression that the cell uses to adapt to different conditions. Given the rich legacy of biological knowledge available for Escherichia coli, the analysis of microarray data poses the challenge of comparing them against the knowledge available in the literature and against computational predictions. Here we present Gene Expression Tools (GETools), a computational environment to analyze expression profiles in Escherichia coli K-12, evaluating their congruence with characterized transcription units, upstream regulatory signals and putative transcriptional factors.
ISSN:0168-9525
DOI:10.1016/S0168-9525(01)02620-8