An electrochemical aptasensor for detection of carbofuran using gold nanoparticles decorated hierarchical porous carbon as an effective sensing platform

• Published in: Chemosphere (Oxford) Vol. 341; p. 140033
• Main Authors: Luo, Lihong, Jiang, Cuiwen, Li, Hu, Ning, Dejiao, Lao, Shuibing, Liang, Zhongdan, Tang, Li, Chen, Weiwei, Ya, Yu
• Format: Journal Article
• Language: English
• Published: Elsevier Ltd 01.11.2023
• Subjects: Carbofuran; Electrochemical aptasensor; Food analysis; Gold nanoparticles decorated hierarchical porous carbon; Carbofuran; Gold nanoparticles decorated hierarchical porous carbon; Electrochemical aptasensor; Food analysis
• ISSN: 0045-6535; 1879-1298
• DOI: 10.1016/j.chemosphere.2023.140033

In this study, a novel electrochemical aptasensor for carbofuran (CBF) detection is prepared by gold nanoparticles decorated hierarchical porous carbon (Au@HPC). The prepared carbon materials show a three-dimensional hierarchical structure with a large specific surface area and a highly developed porous structure. Aptamers loading significantly improves when gold nanoparticles are embedded into the hierarchical porous carbon skeleton. Besides, Au@HPC modified electrode exhibits a large electroactive area and excellent electrochemical conductivity, serving as a promising platform for highly sensitive and selective electrochemical detection of CBF. The developed CBF electrochemical aptasensor shows a wide linear from 1.0 to 100000 pg/L with a detection limit of 0.5 pg/L, demonstrating an extraordinary sensitivity compared to other sensors for CBF detection. Additionally, the designed aptasensor was used to monitor the CBF in vegetable samples, with a recovery range from 98.4% to 104.8%. The results coincide with the standard test method, revealing its practicability in the food safety analysis. [Display omitted] •A gold nanoparticles decorated hierarchical porous carbon (Au@HPC) was prepared and used to construct electrochemical aptasensor firstly.•Au@HPC showed excellent electrochemical performance and aptamers fixation ability.•The developed aptasensor showed much better analytical properties toward carbofuran compared with previously reported sensors.