3′-[(1 H -Indol-3-yl)carbonyl]-1′-methyl-2-oxo-4′-(thiophen-2-yl)spiro[indoline-3,2′-pyrrolidine]-3′-carbonitrile

• Published in: Acta crystallographica. Section E, Structure reports online Vol. 69; no. 10; p. o1585
• Main Authors: Inglebert, S. Antony, Arun, Yuvaraj, Sethusankar, K., Perumal, Paramasivam T.
• Format: Journal Article
• Language: English
• Published: International Union of Crystallography 01.10.2013
• ISSN: 1600-5368; 1600-5368
• DOI: 10.1107/S1600536813025890

In the title compound, C26H20N4O2S, the central pyrrolidine ring adopts a twist conformation on the C-C bond involving the spiro C atom. Its mean plane makes dihedral angles of 78.83 (14), 65.91 (15) and 44.49 (18)° with the mean planes of the adjacent oxindole ring system, the indole system and the thiophene ring, respectively. The indole and indoline units are essentially planar, with maximum deviations of 0.019 (3) and 0.090 (3) Å, respectively. In the oxindole fused-ring system, the pyrrole ring adopts an envelope conformation with the spiro C atom as the flap. In the crystal, pairs of N-H...O hydrogen bonds link the molecules, forming inversion dimers with an R22(8) ring motif. The dimers are linked by further N-H...O hydrogen bonds, forming a two-dimensional network lying parallel to (100).