C(5)—H arylation of 1-substituted 1,2,4-triazoles with aryl halides under Pd/NHC catalysis
An efficient method for the synthesis of 1-substituted 5-aryl-1,2,4-triazoles by selective C—H arylation of 1-substituted 1,2,4-triazoles with non-activated aryl chlorides and aryl bromides under the catalysis by a palladium complex with a N-heterocyclic carbene ligand IPr *OMe using 1,1,2,2-tetraph...
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Published in | Russian chemical bulletin Vol. 73; no. 4; pp. 950 - 956 |
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Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
New York
Springer US
01.04.2024
Springer Nature B.V |
Subjects | |
Online Access | Get full text |
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Summary: | An efficient method for the synthesis of 1-substituted 5-aryl-1,2,4-triazoles by selective C—H arylation of 1-substituted 1,2,4-triazoles with non-activated aryl chlorides and aryl bromides under the catalysis by a palladium complex with a N-heterocyclic carbene ligand IPr
*OMe
using 1,1,2,2-tetraphenylethane-1,2-diol (TPEDO) as a catalyst activator is reported. |
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ISSN: | 1066-5285 1573-9171 |
DOI: | 10.1007/s11172-024-4207-9 |