Marginal Zone B-cell Lymphoma of the Gasserian Ganglion: Case Report and Review of the Literature

• Published in: Arquivos brasileiros de neurocirurgia Vol. 43; no. 1; pp. e76 - e80
• Main Authors: Hegazy, Ahmed, Al-Shami, Hieder, Arundhatai, Biswas, Fathy, Mohammed, Salah, Ahmed M., Aboul-Ela, Hashem, Alsawy, Mohamed F.M., Elkatatny, Amr Mostafa
• Format: Journal Article
• Language: English
• Published: Thieme Revinter Publicações Ltda 01.03.2024
• Subjects: dor facial; facial pain; linfoma primário do sistema nervoso central; neuropatia trigeminal; primary lymphoma of the central nervous system; trigeminal neuropathy
• ISSN: 0103-5355; 2359-5922
• DOI: 10.1055/s-0041-1731064

Abstract Primary central nervous system lymphoma (PCNSL) is a rare subtype of extranodal non-Hodgkin's lymphoma that accounts for 4% of newly diagnosed central nervous system (CNS) tumors. Most primary lymphomas of the central nervous system are of the subtype of diffuse large B-cell lymphomas, which have highly aggressive behavior and may involve the brain, leptomeninges, eyes or spinal cord without evidence of systemic disease. Primary CNS lymphomas are very rare in immunocompetent patients, but their rates are increasing. So far, only 11 primary Gasser ganglion lymphomas have been reported, with an incidence of 2.5 cases per 30,000,000 inhabitants. However, B cell lymphomas of the marginal zone of the Gasserian ganglion have been very rarely reported. We report here a clinical presentation characteristic of B cell lymphoma of the marginal zone of the Gasser ganglion in an immunocompetent patient who was treated with surgery and radiotherapy, evolving with improvement of symptoms and without recurrence in 3 months of follow-up.