Synthesis, characterization, and antimicrobial studies of some palladium complexes with an octamethyl tetraazacyclotetradecadiene ligand and isomers of its reduced form

• Published in: Journal of the Iranian Chemical Society Vol. 15; no. 9; pp. 1947 - 1959
• Main Authors: Palit, Provi, Rabi, Saswata, Dey, Benu Kumar, Palit, Debashis, Uddin, Monir, Roy, Tapashi Ghosh
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.09.2018; Springer Nature B.V
• Subjects: Acetone; Analytical Chemistry; Antibacterial materials; Biochemistry; Chemical synthesis; Chemistry; Chemistry and Materials Science; Coordination compounds; Crystallization; Fractional crystallization; Fungicides; Infrared radiation; Inorganic Chemistry; Isomers; Ligands; Nitrogen dioxide; NMR; Nuclear magnetic resonance; Organic Chemistry; Original Paper; Palladium; Physical Chemistry; Substitution reactions; Xylene; Spectral data; Azamacrocyclic ligands; Axial addition and substitution; Palladium(II); Antimicrobial activities
• ISSN: 1735-207X; 1735-2428
• DOI: 10.1007/s13738-018-1392-1

Biologically important tetraaza-macrocyclic ligand 3,10-C-meso-3,5,7,7,10,12,14,14-octamethyl-1,4,8,11-tetraazacyclotetradeca-4,11-diene dihydroperchlorate, Me 8 [14]diene·2HClO 4 (L 1 ·2HClO 4 ) was synthesized by the condensation of 1,2-diaminopropane with acetone in presence of quantitative amount of HClO 4 and three isomeric ligands designated as L A , L B and L C were separated by the reduction of L 1 ·2HClO 4 with NaBH 4 and fractional crystallization from xylene. The nitrato, nitro, bromido, and iodido complexes of palladium with diene ligand L 1 were prepared by the interaction of L 1 ·2HClO 4 with K 2 [Pd(NO 3 ) 4 ], K 2 [Pd(NO 2 ) 4 ], K 2 [PdBr 4 ], and K 2 [PdI 4 ] (prepared by the reactions with PdCl 2 with KNO 3 , KNO 2 , KBr, and KI, respectively), respectively. The bromide and iodido complexes of L A were prepared by the axial substitution reactions with [PdL A Cl 2 ]Cl 2 . By contrast, similar complexes of other isomeric ligands L B and L C were prepared by axial addition reactions of [PdL ʹ ][PdCl 4 ] (L′ = L B or L C ) with KBr and KI, respectively. The complexes were characterized on the basis of elemental analysis: IR, 1 H-NMR, UV–Vis spectroscopic analysis, and magnetic and molar conductivity data. The antifungal and antibacterial activities of these compounds have been studied against some phyto-pathogenic fungi and bacteria.