The NMR study of human biological fluids for detection of pathologies NMR study of biological fluids

The paper deals with the NMR spectra obtained using preparations of five different human biological body fluids. Characteristic metabolite signals of blood, urine, tears, saliva, and sweat spectra have been determined and classified. The biological body fluid samples were used for search and identif...

Full description

Saved in:
Bibliographic Details
Published inBiochemistry (Moscow). Supplement. Series B, Biomedical chemistry Vol. 8; no. 2; pp. 143 - 149
Main Authors Beskaravainy, P. M., Molchanov, M. V., Suslikov, A. V., Paskevich, S. I., Kutyshenko, V. P., Vorob’ev, S. I.
Format Journal Article
LanguageEnglish
Published Moscow Pleiades Publishing 01.04.2014
Springer Nature B.V
Subjects
Biomarkers
Bioorganic Chemistry
Body fluids
Chemistry
Chemistry and Materials Science
Medicinal Chemistry
NMR
Nuclear magnetic resonance
Pathology
NMR
biomarkers
biological fluids
Online AccessGet full text

Cover

More Information
Summary:The paper deals with the NMR spectra obtained using preparations of five different human biological body fluids. Characteristic metabolite signals of blood, urine, tears, saliva, and sweat spectra have been determined and classified. The biological body fluid samples were used for search and identification of biomarkers of cardiovascular disease. Absolute functional biomarkers for diseases such as coronary heart disease (CHD) have not been recognized even in the case acute myocardial infarction. A hypothesis explaining reasons of lack of such markers has been formulated. The results of comparative analysis of blood and urine samples from humans and some laboratory animals are given. Identify and analyze signals of metabolites of pathogenic microflora and their dynamics in the urine from patients with urogenital diseases have been determined and analyzed and characteristic biomarkers have been recognized.
ISSN:1990-7508
1990-7516
DOI:10.1134/S1990750814020024