Effect of Pulsed Electron Beam Treatment on the Release Profile of Chloramphenicol from Polylactic Acid–Based Polymeric Scaffolds

The paper presents the results of testing the properties of antibacterial nonwoven fibrous materials based on polylactic acid with incorporated chloramphenicol. It has been shown that exposure to a pulsed electron beam increased the rate of release of chloramphenicol into a phosphate-buffered saline...

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Bibliographic Details
Published inHigh energy chemistry Vol. 57; no. 3; pp. 227 - 230
Main Authors Volokhova, A. A., Ponomarev, D. V., Kurzina, I. A., Tverdokhlebov, S. I.
Format Journal Article
LanguageEnglish
Published Moscow Pleiades Publishing 01.06.2023
Springer Nature B.V
Subjects
Chemistry
Chemistry and Materials Science
Chloromycetin
Electron beam processing
Physical Chemistry
Polylactic acid
Radiation Chemistry
pulsed electron beam
polymer modification
biodegradable polymers
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Summary:The paper presents the results of testing the properties of antibacterial nonwoven fibrous materials based on polylactic acid with incorporated chloramphenicol. It has been shown that exposure to a pulsed electron beam increased the rate of release of chloramphenicol into a phosphate-buffered saline medium. In this case, the amount of the substance released from treated samples was reliably greater than that with untreated samples during the five days of the experiment.
ISSN:0018-1439
1608-3148
DOI:10.1134/S0018143923030177