Association of Ischemic Heart Disease Assessed by Radionuclide Myocardial Perfusion Imaging with Bone Mineral Density Measurements by Dual-Energy X-Ray Absorptiometry and Serum Vitamin D Deficiency

Background: Because of the increasing prevalence of both ischemic heart diseases and vitamin D deficiency and also due to recent evidences on association between these two phenomena, it is vital to clarify the association of ischemic heart disease with vitamin D deficiency and low bone mass. Objecti...

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Published inIranian journal of radiology Vol. inpress; no. inpress
Main Authors Izadyar, Sina, Farzanehfar, Saeed, Ranji Amjad, Mina, Abbasi, Mehrshad, Emami Ardekani, Alireza, Fallahi, Babak, Fard Esfehani, Armaghan, Esmaeli, Javad, Akhzari, Fariba, Geramifar, Parham
Format Journal Article
LanguageEnglish
Published Tehran Tehran University of Medical Sciences 01.04.2017
Subjects
Adequacy
Atherosclerosis
Background radiation
Bone density
Calcification
Cardiomyocytes
Cardiovascular disease
Coronary vessels
Defects
Energy measurement
Exercise
Family medical history
Gene expression
Heart diseases
Ischemia
Medical imaging
Mens health
Mortality
Osteoporosis
Patients
Physical fitness
Radioisotopes
Standard deviation
Studies
Vitamin D
Vitamin deficiency
Womens health
Young adults
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Summary:Background: Because of the increasing prevalence of both ischemic heart diseases and vitamin D deficiency and also due to recent evidences on association between these two phenomena, it is vital to clarify the association of ischemic heart disease with vitamin D deficiency and low bone mass. Objectives: The aim of the present study was to assess the relationship between low serum vitamin D and low bone mass measured by dual-energy X-ray absorptiometry (DEXA) with ischemic heart disease assessed by the functional radionuclide myocardial perfusion imaging (MPI). Patients and Methods: In this cross-sectional study, 204 consecutive patients aged older than 50 years who were candidates for MPI were included. Blood sample was extracted to measure the level of serum 25-OH vitamin D using a special kit (IDS kit). Then, the patients were assessed by MPI. Within a month of myocardial perfusion scanning, subjects underwent bone mineral density (BMD) measurements by DEXA method. Results: There was no significant difference in serum level of vitamin D between patients with normal and those with abnormal MPI results. In addition, no significant correlation was detected between BMD and myocardial ischemia. Conclusion: Coronary atherosclerosis may not be associated with the severity of low bone mass or level of vitamin D adequacy.
ISSN:1735-1065
2008-2711
DOI:10.5812/iranjradiol.38221