Choroidal malignant melanoma in patients with oculodermal melanocytosis： report of three cases

• Published in: Chinese medical journal Vol. 123; no. 1; pp. 111 - 113
• Main Authors: Yang, Qiong, Wei, Wen-bin, Yang, Wen-li, Li, Bin, Wang, Guang-lu
• Format: Journal Article
• Language: English
• Published: China Eye Center, Beijing Tongren Hospital, Capital Medical University,Beijing 100730, China 05.01.2010
• Subjects: Aged; Choroid Neoplasms - diagnosis; Choroid Neoplasms - etiology; Female; Humans; Male; Melanoma - diagnosis; Melanoma - etiology; Middle Aged; Nevus of Ota - complications; 危险因素; 恶性黑色素瘤; 神经分布; 脉络膜; 色素沉着; 色素沉积; 黑色素细胞; oculodermal melanocytosis; malignant melanoma; choroidal
• ISSN: 0366-6999; 2542-5641
• DOI: 10.3760/cma.j.issn.0366-6999.2010.01.021

Oculodermal melanocytosis （ODM） is a congenital melanocytic pigmentary disorder involving eyetissue. It is a congenital ocular pigmentation with associated melanocytic deposition in the surrounding dermis. In 1939, Ota and Taninol first gave a definitive description of cutaneous hyperpigmentation along the trigeminal nerve distribution in addition to bulbar involvement, called oculodermal melanocytosis （nevus of Ota）. Oculodermal melanocytosis is a well-recognized risk factor for the development of choroidal malignant melanoma, especially in white patients. Gonder et al2,3 reported ODM is about 35 times more common in the uveal melanoma population. We report three cases of choroidal malignant melanoma in oculodermal melanocytosis patients.