Management of a Patient with Cardiovascular Disease Should Include Assessment of Primary and Secondary Immunodeficiencies: Part 1-Primary Immunodeficiencies

Cardiovascular diseases are some of the most prevalent chronic diseases that generate not only high social but also economic costs. It is becoming increasingly crucial to take into account inborn errors of immunity (IEIs, formerly known as primary immunodeficiencies (PIDs)) and secondary immunodefic...

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Published inHealthcare (Basel) Vol. 12; no. 19; p. 1976
Main Authors Napiórkowska-Baran, Katarzyna, Doligalska, Agata, Drozd, Magdalena, Czarnowska, Marta, Łaszczych, Dariusz, Dolina, Marcin, Szymczak, Bartłomiej, Schmidt, Oskar, Bartuzi, Zbigniew
Format Journal Article
LanguageEnglish
Published Switzerland MDPI AG 04.10.2024
MDPI
Subjects
Aneurysms
Antibodies
Atherosclerosis
Cardiovascular disease
Congenital diseases
Hypertension
Immune system
Immunity (Disease)
Immunology
Infections
Mortality
Mutation
Patients
Quality of life
Review
secondary immunodeficiencies
inborn errors of immunity
primary immunodeficiencies
cardiovascular diseases
immune defects
heart diseases
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Summary:Cardiovascular diseases are some of the most prevalent chronic diseases that generate not only high social but also economic costs. It is becoming increasingly crucial to take into account inborn errors of immunity (IEIs, formerly known as primary immunodeficiencies (PIDs)) and secondary immunodeficiencies (SIDs) in the diagnostic and therapeutic management of cardiac patients. The number of diseases classified as IEIs is on the rise, with a current total of 485. It is essential to pay attention not only to already confirmed conditions but also to symptoms suggestive of immunodeficiencies. The aim of this article is to present IEIs with cardiovascular symptoms that may cause or exacerbate cardiovascular disease, as well as diagnostic and therapeutic procedures. It is becoming increasingly evident that immunodeficiencies can be responsible for certain cardiovascular conditions, their hastened progression, and difficulties in their control. Early detection of deficiencies improves not only the quality and longevity of patients, but also allows for better control of cardiovascular diseases and even prevention of their occurrence.
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ISSN:2227-9032
2227-9032
DOI:10.3390/healthcare12191976