Problems in the Diagnostics and Treatment of Transtiretinum Amyloidosis with Heart Disease in the Elderly: Clinical Experience

The article presents a modern understanding of the treatment of cardiac amyloidosis and provides data on the frequency of occurrence, classification, and variants of clinical manifestations of transthyretin amyloidosis. This pathology is a slowly progressive disease, the symptoms of which usually ap...

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Published inAdvances in gerontology Vol. 9; no. 4; pp. 466 - 471
Main Authors Boldueva, S. A., Petrova, V. B., Khavinson, V. Kh, Samohvalova, M. V., Petrova, A. I.
Format Journal Article
LanguageEnglish
Published Moscow Pleiades Publishing 01.10.2019
Springer Nature B.V
Subjects
Amyloidosis
Cardiomyopathy
Cardiovascular disease
Carpal tunnel syndrome
Clinical trials
Geriatrics/Gerontology
Heart failure
Liver transplants
Medicine
Medicine & Public Health
Mutation
Pathology
Patients
Proteins
Toxicity
heart failure
“wild-type” amyloidosis
cardiomyopathy
transthyretin amyloidosis
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Summary:The article presents a modern understanding of the treatment of cardiac amyloidosis and provides data on the frequency of occurrence, classification, and variants of clinical manifestations of transthyretin amyloidosis. This pathology is a slowly progressive disease, the symptoms of which usually appear in elderly and senile age. This diagnosis may become more common in the future as the population ages and diagnostic methods improve. A description of the clinical case of transtritin amyloidosis of the heart in a 77-year-old patient, which occurred with a primary lesion of the heart and symptoms of chronic heart failure, is given as an illustration that shows the difficulties in the lifetime diagnosis of transthyretin amyloidosis.
ISSN:2079-0570
2079-0589
DOI:10.1134/S2079057019040039