Assessing the Efficiency of Rapid Methods for Evaluating Selectivity and Analytical Signal Strength in Various Fluorescent Phases

• Published in: Journal of analytical chemistry (New York, N.Y.) Vol. 79; no. 5; pp. 614 - 627
• Main Authors: Kuchmenko, T. A., Vandyshev, D. Yu, Yagov, V. V., Umarkhanov, R. U., Ledneva, I. V.
• Format: Journal Article
• Language: English
• Published: Moscow Pleiades Publishing 01.05.2024; Springer Nature B.V
• Subjects: Adsorption; Alcohols; Aldehydes; Amines; Ammonia; Analytical Chemistry; Biomarkers; Cadmium sulfide; Chemistry; Chemistry and Materials Science; Chitosan; Consistency; Fluorescence; Fluorimetry; Ketones; Mathematical analysis; Organic semiconductors; Phases; Photoluminescence; Piezoelectricity; Quantum dots; Reagents; Signal strength; Substrates; Test systems; VOCs; Volatile organic compounds; quantum dots; adsorption; spectroscopy; fluorescence; informativeness; organic biomolecules; organic reagents
• ISSN: 1061-9348; 1608-3199
• DOI: 10.1134/S106193482405006X

The results of evaluating the adsorption and fluorescent properties of azolotriazine compounds and phases based on cadmium sulfide quantum dots in vapors of volatile organic compounds (biomarkers of living systems) are considered. The adsorption properties of phases based on organic dyes and encapsulated semiconductors towards vapors of alcohols, ketones, amines, acids, ammonia, and aldehydes are investigated using direct high-sensitivity piezoelectric quartz microweighing. The spectral properties and their variations in analyte vapors are investigated using various spectroscopy methods (absorption, photoluminescence). The research results are compared, and the potential for optimizing this stage is assessed. It is proposed to evaluate the consistency of methods for predicting changes in fluorescent properties in test systems for volatile organic compounds using the Kendall coefficient of concordance, W . The highest level of agreement ( W = 0.89) was observed between the methods of spectrofluorimetry and direct vapor microweighing upon adsorption on phases being potential fillers of test systems. A correlation between the results obtained by different fluorescence methods (visual plate test systems and fluorimetry of phases on paper substrates) is 0.80, which confirms a high degree of consistency in assessments using them in the degree of interaction between the analytes and organic, combined fluorochromes. The methods closely related in the nature of the analytical response do not exhibit better agreement than the method of direct vapor microweighing on microphases of fluorimetric reagents of different nature (cadmium sulfide quantum dots/chitosan, organic azolotriazine compounds, mixed phases). This, in turn, enables the selection of simpler, more available, and more rapid methods and means of analysis in routine experiments.