Preparation of Nanocapsules with Alginate/Polylysine Complex Wall

This paper deals with a novel preparation method of nanocapsules with alginate/polylysine complex wall. The preparation method consisted of the following steps: dispersion of an aqueous sodium alginate solution into cyclohexane to give a W/O emulsion, preparation of calcium alginate gel beads by add...

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Bibliographic Details
Published inJournal of Oleo Science Vol. 55; no. 12; pp. 615 - 621
Main Authors ABE, Masahiko, TANAKA, Kensuke, NAKAYAMA, Ai, KONDO, Tamotsu, TSUCHIYA, Koji, TANTAYAKOM, Veerapat, OHKUBO, Takahiro, SAKAI, Hideki
Format Journal Article
LanguageEnglish
Published Tokyo Japan Oil Chemists' Society 2006
Japan Science and Technology Agency
Subjects
alginate
electrocapillary emulsification
nanocapsule
polylysine
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Summary:This paper deals with a novel preparation method of nanocapsules with alginate/polylysine complex wall. The preparation method consisted of the following steps: dispersion of an aqueous sodium alginate solution into cyclohexane to give a W/O emulsion, preparation of calcium alginate gel beads by adding the emulsion into a calcium aerosol OT solution in cyclohexane, and alginate/polylysine complex wall formation on the surface of calcium alginate beads by adding the beads into an aqueous poly-L-lysine solution. The size of alginate/polylysine complex capsules thus prepared was found to be 100-500 nm. Moreover, an attempt was made to prepare much smaller capsules using a laboratory-made apparatus for electrocapillary emulsification and the capsule size could be reduced to about 40 nm.
ISSN:1345-8957
1347-3352
DOI:10.5650/jos.55.615