A Case of Diabetic Chorea Secondary to Appetite Loss Due to COVID-19 Vaccination

A 76-year-old woman with type 2 diabetes mellitus was admitted to our hospital with a complaint of involuntary movements of the limbs and face. Brain MRI demonstrated a bilateral high signal of putamen on the T1 weighted image, and she was diagnosed with diabetic chorea. She took a second dose of th...

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Published inCurēus (Palo Alto, CA) Vol. 15; no. 11; p. e49138
Main Authors Inoue, Hideyuki, Kusano, Eiji, Shinkai, Yasuhiro, Ito, Hiroyuki
Format Journal Article
LanguageEnglish
Published United States Cureus Inc 20.11.2023
Cureus
Subjects
Alzheimer's disease
Carbon monoxide poisoning
Cardiac arrest
Case reports
COVID-19 vaccines
Diabetes
Disease transmission
Endocrinology/Diabetes/Metabolism
Glucose
Hematoma
Hemoglobin
Hospitals
Hyperglycemia
Immunization
Insulin
Internal Medicine
Medical imaging
Metabolism
mRNA vaccines
Neurology
Patients
Peptides
Potassium
Severe acute respiratory syndrome coronavirus 2
covid-19
mrna vaccine
involuntary movement
diabetes mellitus
diabetic chorea
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Summary:A 76-year-old woman with type 2 diabetes mellitus was admitted to our hospital with a complaint of involuntary movements of the limbs and face. Brain MRI demonstrated a bilateral high signal of putamen on the T1 weighted image, and she was diagnosed with diabetic chorea. She took a second dose of the COVID-19 vaccine 28 days before admission and lost her appetite. Consequently, her HbA1c level on admission decreased from 13.5% to 10.0% in 28 days. This case suggests that diabetic chorea could be induced by the rapid amelioration of a hyperglycemic state due to appetite loss after COVID-19 mRNA vaccination.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.49138