An Uncommon Side Effect of Rivaroxaban: A Drug-Induced Liver Injury

Rivaroxaban is rarely associated with drug-induced liver injury (DILI). A 57-year-old male was sent to the emergency room from an endocrine clinic for a presyncope evaluation. His exam was non-focal, and his laboratory work was remarkable for the hepatocellular pattern of liver injury. Upon detailed...

Full description

Saved in:
Bibliographic Details
Published inCurēus (Palo Alto, CA) Vol. 15; no. 9; p. e45949
Main Authors Karki, Bhesh R, Jasaraj, Ranjit B, Jha, Suman K, Maisuradze, Nodari, Yu, Qi
Format Journal Article
LanguageEnglish
Published United States Cureus Inc 25.09.2023
Cureus
Subjects
Antibodies
Anticoagulants
Antigens
Blood pressure
Cardiac arrhythmia
Disease prevention
Emergency medical care
Enzymes
Gastroenterology
Health sciences
Hematology
Hepatitis B
Hospitals
Immunoglobulins
Internal Medicine
Ischemia
Laboratories
Liver
Phosphatase
Stroke
Thyroid gland
United States > US
Chicago Illinois
New York City New York
drug induced liver injury
rivaroxaban
elevated transaminases
deranged liver function tests
hepatotoxicity
direct oral anticoagulant
Online AccessGet full text

Cover

More Information
Summary:Rivaroxaban is rarely associated with drug-induced liver injury (DILI). A 57-year-old male was sent to the emergency room from an endocrine clinic for a presyncope evaluation. His exam was non-focal, and his laboratory work was remarkable for the hepatocellular pattern of liver injury. Upon detailed assessment, he was found to have DILI due to rivaroxaban. The liver function tests improved after its discontinuation. This case emphasizes the need for early recognition and timely intervention to prevent further hepatotoxicity from the culprit drug.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.45949