Primary Circumscribed Meningeal Melanoma Involving the Meckel's Cave: A Report of a Rare Case and Review of Literature

Primary intracranial meningeal melanomas are rare. Diagnosing primary meningeal melanomas mostly involves comprehensive assessment through clinical and radiological means. This evaluation should encompass a detailed dermal and ophthalmic examination. Any suspicious lesion must be biopsied and examin...

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Published inCurēus (Palo Alto, CA) Vol. 16; no. 3; p. e55427
Main Authors Tajammul, Syeda Sara, Rassou, Salim Chaib, Munir, Javeria, Ahmed, Zubair, Nadaf, Asma Naaz
Format Journal Article
LanguageEnglish
Published United States Cureus Inc 03.03.2024
Cureus
Subjects
Brain cancer
Histopathology
Melanoma
Metastasis
Oncology
Pathology
Patients
Radiation therapy
Radiology
Skin cancer
Tumors
primary meningeal melanocytic tumors
meckel’s cave
melanoma
circumscribed
pigmented
trigeminal
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Summary:Primary intracranial meningeal melanomas are rare. Diagnosing primary meningeal melanomas mostly involves comprehensive assessment through clinical and radiological means. This evaluation should encompass a detailed dermal and ophthalmic examination. Any suspicious lesion must be biopsied and examined microscopically. This is crucial not only to differentiate primary intracranial melanoma from other brain tumors but also to rule out metastases from potential sources of primary cutaneous or non-cutaneous melanomas. Surgery is considered the mainstay of treatment. Despite melanomas being generally considered radio- and chemo-resistant tumors, adjuvant radiotherapy and chemotherapy still play a crucial role in their management. The treatment landscape for primary meningeal melanoma is continually evolving, with ongoing research aiming to improve outcomes for patients with this challenging disease.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.55427