Hyperviscosity Syndrome in Undifferentiated Connective Tissue Disease: A Diagnostic and Therapeutic Challenge

Hyperviscosity is an uncommon manifestation of various underlying diseases. Rapid diagnosis and management of the underlying disease is crucial to prevent significant complications, including hypertension, cerebral vascular accidents, pulmonary embolism, bowel ischemia, and ophthalmologic pathologie...

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Published inCurēus (Palo Alto, CA) Vol. 16; no. 3; p. e55399
Main Authors Mines, Ian, Al-Abayechi, Alaq, Kaur, Supreet, Nooruddin, Zohra
Format Journal Article
LanguageEnglish
Published United States Cureus Inc 02.03.2024
Cureus
Subjects
Adenosine diphosphate
Anemia
Antibodies
Apheresis
Biopsy
Blood diseases
Blood platelets
Bone marrow
Collagen
Connective tissue diseases
Creatinine
Cytomegalovirus
Dehydrogenases
Etiology
Hematology
HIV
Human immunodeficiency virus
Immunoglobulins
Internal Medicine
Kinases
Leukemia
Lupus
Lymphatic system
Medical diagnosis
Multiple myeloma
Peptides
Proteins
Rheumatoid arthritis
Rheumatology
Viscosity
rash
plex
hyperviscosity syndrome
undifferentiated connective tissue disorder (uctd)
epistaxis
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Summary:Hyperviscosity is an uncommon manifestation of various underlying diseases. Rapid diagnosis and management of the underlying disease is crucial to prevent significant complications, including hypertension, cerebral vascular accidents, pulmonary embolism, bowel ischemia, and ophthalmologic pathologies. Although the acute management of complications arising from hyperviscosity is relatively straightforward, identifying and treating the underlying cause can prove difficult. This case highlights the difficulties of establishing a diagnosis and initiating appropriate management for a patient with hyperviscosity syndrome in a suspected rheumatologic disorder.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.55399