Glutaraldehyde-Induced Allergic Contact Dermatitis: A Case Report and Safety Standards

Glutaraldehyde (GA), a potent disinfectant and sterilizing agent extensively used in healthcare settings, has garnered attention for its association with contact dermatitis. This occupational skin condition, often induced by repeated exposure to GA, poses significant challenges to the well-being of...

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Bibliographic Details
Published inCurēus (Palo Alto, CA) Vol. 16; no. 3; p. e56954
Main Authors Pandey, Pragya, Bharti, Ramesh, Jasrasaria, Neha
Format Journal Article
LanguageEnglish
Published United States Cureus Inc 26.03.2024
Cureus
Subjects
Allergy/Immunology
Case reports
Dentistry
Dermatitis
Disinfection & disinfectants
Endodontics
Gloves
Medical personnel
Occupational safety
Rubber
Safety standards
Zinc oxides
Switzerland
contact dermatitis
allergic reaction
occupational risk exposure
glutaraldehyde
delayed hypersensitivity
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Summary:Glutaraldehyde (GA), a potent disinfectant and sterilizing agent extensively used in healthcare settings, has garnered attention for its association with contact dermatitis. This occupational skin condition, often induced by repeated exposure to GA, poses significant challenges to the well-being of healthcare professionals and patients alike. Understanding the causes, symptoms, and preventive measures against GA-induced contact dermatitis is essential for promoting a safe and healthy working environment in healthcare facilities. A 28-year-old female presented with a severe burning sensation and dark brown patches in the lower chin region, one day following root canal treatment. Based on the characteristic appearance of patches and the typical burning sensation associated with an allergic reaction, a diagnosis of acute contact dermatitis was made. Patch testing by an expert dermatologist confirmed that the patient was allergic to GA. GA, a popular commercial germicidal product, is widely used as a cold sterilizing agent for operative dental instruments. The patient developed a reaction as the endodontic files used during the root canal procedure were cold sterilized with 2% GA. The lesion experienced significant improvement and ultimately healed following the administration of corticosteroids and antihistamines. This report concerns a case of GA-induced contact dermatitis. As GA is being used more widely, particularly in dental clinics, this case was of interest and is reported in the safety interest of patients and clinicians.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.56954